The clash featuring Manchester United and Manchester City arguably is the highlight of matchday 11, but there are plenty of other big games you won't want to miss.

The latest batch of Premier League games is set to get underway shortly, with Southampton and Aston Villa kicking off proceedings on Friday evening. Many eyes will certainly be peeled for the highly-anticipated clash between Manchester United and Manchester City, but there are other major games to tune into. These include Tottenham's away match against Everton, with Antonio Conte looking to revive the London club's fortunes, while Liverpool and Chelsea will also be in action against West Ham and Burnley respectively.

Here's all you need to know ahead of matchday 11.

Premier League standings heading into matchday 11

Premier League games you won't want to miss on matchday 11

Manchester United vs Manchester City: The latest installment of the Manchester Derby arguably will be the highlight game of matchday 11 as bitter cross-town rivals Manchester United and Manchester City battle for not just three points, but bragging rights. Only three points separate the two sides ahead of this contest. The Red Devils come into this match having ended their four game winless streak by picking up a resounding 3-0 road win over Tottenham - which likely was the saving grace for Ole Gunnar Solskjaer's job.

By contrast, the Cityzens saw their four match unbeaten streak snapped during a shock 2-0 away loss to a Crystal Palace side who, prior to that result, had picked up just four points from their prior quartet of matches. Both Solskjaer and Pep Guardiola will certainly be under pressure to clinch a much needed win here, especially with teams like West Ham looking to upset the proverbial apple cart. Indeed, this match, like several others this weekend, could see some major shake-ups in the race for a top four berth.

Chelsea vs Burnley: On top of the table, Chelsea have been simply fantastic in the Premier League this season. The Blues have conceded a measly three goals, making their defense by far the strongest in the league, but they certainly won't want to leave anything to chance when Burnley arrive at Stamford Bridge. Thomas Tuchel's troops are on a four game winning streak in the league, but will have to do without key man Romelu Lukaku, but have been given a major boost with star midfielder N'Golo Kante now recovering from an ankle injury just in time for this weekend's game.

Burnley, meanwhile, finally won their first game of the season last time out, but still sit in 18th spot, with a measly seven points earned from their first ten games. The Clarets have a frustrating record against Chelsea, as they've failed to win any of their last six meetings across all comps, and on a personal level, current Burnley boss Sean Dyche has his own Chelsea hoodoo, with just one win from his prior 12 meetings against the London giants.

Arsenal vs Watford: Their dark days seemingly behind them for good, Arsenal have been slowly creeping up the table due to some positive results. The Gunners will next take on Watford, who sit dangerously close to the drop zone having won just one of their last five games. With a top four spot in their sights, Arsenal will naturally look to exploit Watford's abysmal form and start to trying to put pressure on the teams presently occupying the coveted Champions League places.

The hosts, for their part, have earned three wins and two draws from their last five Premier League games, and will certainly be brimming with confidence ahead of Watford's arrival to the Emirates this weekend.

Everton vs Tottenham: This game will be significant as it's set to be Antonio Conte's first match in charge since taking over from the sacked Nuno earlier this week. As things stand, Tottenham have lost three of their last five games, including two in a row and sit in ninth place, ten points behind league leaders Chelsea and five away from the Champions League places.

On their heels are Everton, who've picked up 14 points, sit in tenth spot, and like Tottenham, have been in a slump lately. The Toffees have won just one of their last five games, and will come into this contest on a three game losing streak. It'll surely be interesting to see if Conte's arrival will be the tonic Tottenham really need, or if Everton, desperate to avoid a fourth straight defeat, come out on top in this encounter.

West Ham vs Liverpool: Liverpool are still the only side yet to lose a game so far this season, but the Reds could face a tricky test when they travel to face West Ham. Jurgen Klopp's men are three points behind league leaders Chelsea, so they will certainly be hoping that the Blues suffer what would be a highly unlikely slip-up against Burnley to pull level on points.

As for West Ham, they're having an absolutely fantastic campaign so far, with four wins from their last five games helping them surge up the table, and in fact, depending on how things pan out, the Hammers could actually find themselves in second spot should they beat Liverpool and Manchester City end up losing to Manchester United. In short, this will be a game not to miss as West Ham hope to make it four wins on the spin and become the first team to beat Liverpool in league action this season.

Team news for matchday 11

Here's who's out or in doubt for matchday 11

*All info as of 4 November 2021

Chelsea: Romelu Lukaku (Ankle/Foot Injury), Timo Werner (Thigh Injury), Mateo Kovacic (Thigh Injury); Doubtful - Mason Mount (Illness)

Liverpool: James Milner (Hamstring Injury), Naby Keita (Hamstring Injury), Roberto Firmino (Hamstring Injury), Joe Gomez (Calf Injury), Harvey Elliott (Ankle/Foot Injury)

Manchester City: Ferran Torres (Ankle/Foot Injury), Aymeric Laporte (Red Card Suspension), Benjamin Mendy (Suspended by club due to police investigation), Kyle Walker (Ankle/Foot Injury)

West Ham: No major injuries or suspensions

Manchester United: Paul Pogba (Red Card Suspension), Raphael Varane (Thigh Injury); Doubtful - Victor Lindelof (Knock)

Tottenham: Ryan Sessegnon (Unspecified Injury), Bryan Gil (Thigh Injury)

Arsenal: Granit Xhaka (Knee Injury), Kieran Tierney (Ankle Injury)

Premier League matchday 11 fixtures